New model of oropharyngeal candidiasis in mice.
نویسندگان
چکیده
We established a straightforward murine model of oropharyngeal candidiasis. Mice were immunosuppressed with cortisone acetate, anesthetized, and then inoculated by placing cotton wool balls saturated with Candida albicans sublingually for 2 h. A prolonged, reproducible infection was induced. This model may be useful for antifungal screening or pathogenesis studies.
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 45 11 شماره
صفحات -
تاریخ انتشار 2001